Psychosomatic Medicine
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

Published online before print February 8, 2007, 10.1097/PSY.0b013e31802f054b
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Grippo, A. J.
Right arrow Articles by Carter, C. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grippo, A. J.
Right arrow Articles by Carter, C. S.

Depression-Like Behavior and Stressor-Induced Neuroendocrine Activation in Female Prairie Voles Exposed to Chronic Social Isolation

Angela J. Grippo, PhD, Bruce S. Cushing, PhD and C. Sue Carter, PhD

From the Department of Psychiatry and Brain-Body Center, University of Illinois at Chicago, Chicago, IL.


Figure 16
View larger version (9K):
[in this window]
[in a new window]

 
Figure 1. Mean (±SEM) absolute water and sucrose intake (A) and mean sucrose preference (B) in paired and isolated prairie voles after 50 days of social isolation. *p < .05 versus respective paired value.

 

Figure 26
View larger version (8K):
[in this window]
[in a new window]

 
Figure 2. (±SEM) number of aggressive episodes during the resident-intruder test (A) and number of agitated behaviors after the resident-intruder test (B) in paired and isolated groups. Note the scale differences in A and B. *p < .05 versus paired value.

 

Figure 36
View larger version (17K):
[in this window]
[in a new window]

 
Figure 3. Mean (±SEM) circulating levels of oxytocin (A), arginine vasopressin (B), ACTH (C), and corticosterone (D) in paired and isolated prairie voles at 10 minutes after a 5-minute resident-intruder test. Note the scale differences among the four panels. *p < .05 versus paired value.

 

Figure 46
View larger version (178K):
[in this window]
[in a new window]

 
Figure 4. Brain sections (40 µm) showing oxytocin- (A and B) and CRF-immunoreactivity (C and D) in representative paired (A and C) and isolated (B and D) prairie voles in the hypothalamic PVN. Pictures are shown at 100x magnification. Scale bars = 100 µm. Stained fibers were excluded from analysis.

 

Figure 56
View larger version (8K):
[in this window]
[in a new window]

 
Figure 5. Mean (±SEM) number of oxytocin- (A) and CRF-immunoreactive (B) cells in the hypothalamic PVN in paired and isolated prairie voles. Note the scale differences in A and B. *p < .05 versus paired value. Stained fibers were excluded from analysis.

 





HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American Psychosomatic Society