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Associations of a Regulatory Polymorphism of Monoamine Oxidase-A Gene Promoter (MAOA-uVNTR) With Symptoms of Depression and Sleep Quality

Beverly H. Brummett, PhD, Andrew D. Krystal, MD, Ilene C. Siegler, PhD, MPH, Cynthia Kuhn, PhD, Richard S. Surwit, PhD, Stephan Züchner, MD, Allison Ashley-Koch, PhD, John C. Barefoot, PhD and Redford B. Williams, MD

From the Department of Psychiatry and Behavioral Sciences (B.H.B., A.D.K., I.C.S., R.S.S., S.Z., J.C.B., R.B.W.), Center for Human Genetics (A.A.-K.), and Department of Pharmacology and Cancer Biology (C.K.), Duke University Medical Center, Durham, North Carolina.


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  		Figure 1. Association of variable number of tandem repeats in the MAOA linked polymorphic region (MAOA-uVNTR) genotypes with symptoms of depression and sleep quality (adjusted means and standard errors). CES-D = Center for Epidemiological Studies of Depression; PSQI = Pittsburgh Sleep Quality Index.

 




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