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The Long and the Short of It: Associations Between 5-HTT Genotypes and Coping With Stress

From the School of Psychiatry (K.W., J.E.S., A.W.F., D.H.-P., P.B.M., G.P.), University of New South Wales and Black Dog Institute, Sydney, Australia; Garvan Institute of Medical Research (P.R.S.), Sydney; University of New South Wales, Sydney; and Prince of Wales Medical Research Institute, Sydney, Australia.

View larger version (9K): [in this window] [in a new window]   Figure 1. Two hypothetical coping models demonstrating (A) the mediating role of coping in the relationship between 5-HTT genotype under exposure to stress and depression, and (B) the relationships between the variables measured in the present study of genotype, gender, and coping. 5-HTT = serotonin transporter.

View larger version (10K): [in this window] [in a new window]   Figure 2. Reported use of CUS problem-solving strategies by gender and 5-HTT genotype. CUS = coping under stress; 5-HTT = serotonin transporter.