Fig. 1. Age and 24-hour testosterone secretion in men with major depression and a healthy comparison group. Linear regression analysis shows an absence of significant correlation between age and 24-hour testosterone secretion in the patient group (r = .11). In the comparison group there is a trend toward a negative correlation between age and 24-hour testosterone (r = -.39; p < .08). ANCOVA reveals significantly lower concentrations in depressed patients (df = 1,33; F = 8.5; p < .001) and a trend for an interaction between age and diagnosis (df = 1,33; F = 3.7; p < .07).
