
Fig. 3. Effects of mood stabilizers on signaling pathways and gene expression. ATP = adenosine triphosphate; CBZ = carbamazepine; Gs = Gi-G proteins mediating stimulation or inhibition of adenylate cyclase; MAPK = mitogen-activated protein kinase; MAPKK = mitogen-activated protein kinase kinase; PKA = protein kinase A; PLCß = phospholipase C ß isozyme; Rq = receptors coupled to G protein Gq; Rs = Ri receptors coupled to stimulation or inhibition of AC; RSK = ribosomal S6 kinase; TrK = receptor tyrosine kinase; VPA = valproate.