Fig. 1. Specific IgM and IgG antibody responses in FSL and FRL rats after immunization with 300 µg/kg KLH. (A) Anti-KLH IgM antibodies increased significantly after immunization: F(5,125) = 20.01, p < .0001. IgM levels were significantly lower in the FSL rats than in FRL controls: F(1,25) = 13.57, p < .01. Data for the 1:10 serum dilution are shown. (B) Anti-KLH IgG antibodies increased significantly after immunization: F(5,120) = 164.50, p < .0001 (IgG response values for one FRL animal were more than 2 SDs from the mean FRL response on each day; these were excluded from statistical analyses). There were no strain differences in IgG production (F(1,24) = 0.59, p = .45), and no strain by day interaction (F(5,120) = 0.49, p = .78). Data for the 1:50 serum dilution are shown. **p < .01, *p < .05.
