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Fig. 1. Interaction of vital exhaustion with pathogen burden on selected measures of hemostasis and inflammation. Group 1 comprised individuals with low stress and low PB (N = 25); group 2 comprised individuals with low stress and high PB or high stress and low PB (intermediate group; N = 13); and group 3 comprised individuals with high stress and high PB (N = 21). Significant linear increases were found in fibrinogen, all fibrinolytic measures (PAI-1:act is shown), and in IL-1ra, IL-6 (data are shown), and IL-10 (all p values < .01). Higher-order trends were not significant (all p values > .10). Data are mean + standard error of mean. The indicated significance levels are those of Bonferroni post hoc multiple comparisons.
