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Fig. 1. A common pathway model for risk of lifetime depression symptoms (DEP sx), hypertension (HBP), and heart disease (HD) in 2,731 male-male twin pairs. The figure illustrates the genetic (A), shared environmental (C), and unique environmental (E) variance component estimates (95% confidence intervals) in common and specific to each phenotype. The "A" at the top of the figure indicates genetic influences common to all three phenotypes. The "A" and "E" at the bottom of the figure indicates genetic and unique environmental influences specific to each phenotype.
