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Figure 4. Hamilton Depression Rating Scale (HAM-D) scores after 16 weeks of treatment using intention-to-treat analysis (left panel) and limited to patients who did not exhibit an early response (n = 183) (right panel). Probability estimates are for a patient with the most typical profile in the study: age 52 years, female, Caucasian, one prior major depressive episode, and a baseline HAM-D score of 17. Error bars represent 95% confidence limits. Planned contrasts for the HAM-D using intention-to-treat analysis yielded the following test results: all active treatment versus placebo, p = .231; all exercise versus medication, p = .574; supervised exercise versus home exercise, p = .624. After removing early responders, the contrast results were: all active treatment versus placebo, p = .123; all exercise versus medication, p = .514; supervised exercise versus home exercise, p = .510. Sup = supervised exercise; Med = medication; Plac = placebo.
